Since September 2001, substances in products regulated under the Food and Drugs Act (F&DA) have been subject to the New Substances Notification Regulations (NSNR) of the Canadian Environmental Protection Act, 1999 (CEPA 1999. Substances which were in products that were regulated under the Food and Drugs Act and that were in Canadian commerce between 01 January 1987 and 13 September 2001 were placed on a list, called the In-Commerce List (ICL) until a regulatory framework could be developed to adequately address them.
The ICL contains substances found in pharmaceuticals, veterinary drugs, biologics and genetic therapies, cosmetics, medical devices and food additives. The ICL is a static list which will not change.
The ICL consists of four sub-lists:
The ICL was compiled from Health Canada records, and while the ICL has been a useful administrative tools, it contained duplications, omissions and inaccurate chemical identifiers. As such, Health Canada recognized the need to revise the ICL in order to resolve its shortcomings. In September of 2010, a Notice of Intent to revise the ICL was published in Canada Gazette Part I.
The revision of the ICL was carried out through:
The Nomination Process for including substances on the revised ICL had two phases. Phase II was completed February 14, 2012. Although the formal Nomination Process for including substances on the revised ICL has ended, any additional nominations to the revised ICL may be submitted and will be reviewed. Health Canada will update the revised ICL on their web site, as required.